RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways

RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways
Author :
Publisher : Academic Press
Total Pages : 463
Release :
ISBN-10 : 9780080923321
ISBN-13 : 0080923321
Rating : 4/5 (321 Downloads)

Book Synopsis RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways by : Lynne E. Maquat

Download or read book RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways written by Lynne E. Maquat and published by Academic Press. This book was released on 2011-09-02 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, and RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. - Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway - Expert researchers introduce the most advanced technologies and techniques - Offers step-by-step lab instructions, including necessary equipment and reagents


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The diversity of RNAs inside living cells is amazing. We have known of the more “classic” RNA species: mRNA, tRNA, rRNA, snRNA and snoRNA for some time now,