Fidelity and Quality Control in Gene Expression

Fidelity and Quality Control in Gene Expression
Author :
Publisher : Academic Press
Total Pages : 267
Release :
ISBN-10 : 9780123864987
ISBN-13 : 0123864984
Rating : 4/5 (984 Downloads)

Book Synopsis Fidelity and Quality Control in Gene Expression by :

Download or read book Fidelity and Quality Control in Gene Expression written by and published by Academic Press. This book was released on 2012-01-25 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this volume is to provide a comprehensive mechanistic and quantitative view of the processes that mediate or influence the quality control in translation. In addition to discussing processes with direct contribution to translation fidelity, such as aminoacylation of tRNAs and translation elongation itself, special attention is given to other processes with impact on quality control: detection and elimination of defective mRNAs, recycling and translation re-initiation, mRNA editing, and translational recoding through programmed frame-shifting. - Provides a comprehensive mechanistic and quantitative view of the processes that mediate or influence the quality control in translation - Special attention is given to other processes with impact on quality control: detection and elimination of defective mRNAs, recycling and translation re-initiation, mRNA editing, and translational recoding through programmed frame-shifting


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By virtue of their role as catalysts of the aminoacylation reaction, the aminoacyl-tRNA synthetases ensure that the first step of translation is performed quick