Faithin Omaha eBook Collection

Download or read book Applications of Domino Transformations in Organic Synthesis, Workbench Edition written by Scott A. Snyder and published by Thieme Chemistry. This book was released on 2016-05-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid pace of evolution in domino, or cascade-based transformations has revolutionized the practice of chemical synthesis for the creation of natural products, designed molecules, and pharmaceuticals. Science of Synthesis: Applications of Domino Transformations in Organic Synthesis explores the topic thoroughly and systematically, serving as the basis for practical applications and future research. The 2-volume set presents the cutting-edge in terms of design, strategy, and experimental procedures, leading to multiple events being accomplished within a single reaction vessel. The content is organized by the core type of reaction used to initiate the event, be it a pericyclic reaction, a metal-mediated transformation, radical chemistry, or an acid-induced cascade among many others. Volume 1 covers polyene/cation-pi cyclizations, metathesis, radical, and metal-mediated reactions, and non-radical skeletal rearrangements. Volume 2 covers pericyclic reactions (Diels-Alder, sigmatropic shifts, ene reactions), dearomatizations, and additions to C-O/C-N multiple bonds.