Post-transcriptional Gene Regulation in Human Disease
Author | : Buddhi Prakash Jain |
Publisher | : Academic Press |
Total Pages | : 396 |
Release | : 2022-08-12 |
ISBN-10 | : 9780323914246 |
ISBN-13 | : 0323914241 |
Rating | : 4/5 (241 Downloads) |
Download or read book Post-transcriptional Gene Regulation in Human Disease written by Buddhi Prakash Jain and published by Academic Press. This book was released on 2022-08-12 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Post-transcriptional Gene Regulation in Human Disease, a new volume in the Translational Epigenetics book series, offers a thorough overview and discussion of post-transcriptional genetic control mechanisms and their roles across various pathologies and human developmental outcomes, along with regulatory mechanisms targeted for therapeutic approaches. The book is broadly divided in two parts: early chapters describe the basics of post-transcriptional gene regulation, associated epigenetic mechanisms, the role of RNA binding proteins, the evolution of post-transcriptional gene regulation, and methods to study these mechanisms. The second half of the book includes deeper discussion of post-transcriptional gene regulation across specific diseases and therapeutics targets. Various post-transcriptional events, including alternative splicing and polyadenylation, mRNA stability, and miRNAs and their involvement in the disease progression, are examined in detail. - Includes full-color imagery illustrating key concepts and post-transcriptional disease processes, as well as descriptions of methods for studying post-transcriptional gene regulation - Presents fundamental knowledge, molecular and biochemical mechanisms, and recent findings in concise and easily understandable formats - Features a summary and conclusion at the end of each chapter