Glycosylation Engineering of Biopharmaceuticals

Glycosylation Engineering of Biopharmaceuticals
Author :
Publisher : Humana Press
Total Pages : 0
Release :
ISBN-10 : 1627033262
ISBN-13 : 9781627033268
Rating : 4/5 (268 Downloads)

Book Synopsis Glycosylation Engineering of Biopharmaceuticals by : Alan Beck

Download or read book Glycosylation Engineering of Biopharmaceuticals written by Alan Beck and published by Humana Press. This book was released on 2013-03-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glyco-engineering is being developed as a method to control the composition of carbohydrates and to enhance the pharmacological properties of monoclonal antibodies (mAbs) and other proteins. In Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols, experts in the field provide readers with production and characterization protocols of glycoproteins and glyco-engineered biopharmaceuticals with a focus on mAbs. The volume is divided in four complementary parts dealing with glyco-engineering of therapeutic proteins, glycoanalytics, glycoprotein complexes characterization, and PK/PD assays for therapeutic antibodies. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols serves as an ideal guide for scientists striving to push forward the exciting field of engineered biopharmaceuticals.


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