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Download or read book Design, Synthesis and Characterization of Chiral CCC-NHC Transition Metal Complexes and Catalytic Activity written by Gopalakrishna Akurathi and published by . This book was released on 2016 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first stable "free" N-heterocyclic carbene (NHC) was isolated in 1991, since then many classes of NHCs were synthesized and isolated. N-heterocyclic carbene ligands have become a common ligand in the synthesis of metal complexes, due to their strong [Sigma]-donation with poor [pi]-acceptor ability. Among all the NHC metal complexes, Hollis group was interested in exploring CCC-NHC pincer complexes. In 2005, Hollis and co-workers synthesized and isolated first achiral CCC-NHC zirconium pincer amido complex and studied its catalytic ability to perform intramolecular hydroamination of aminoalkenes. Later, Hollis group designed and developed new NHCs with a saturated chiral backbone, and used these new ligands to generate a new series of metal complexes. This dissertation is focused on the design, synthesis and characterization of several chiral bi-dentate NHC ligands with varying substituents on the backbone. These NHC ligands were used to synthesize several chiral mono, bis and tris amido CCC-NHC zirconium pincer complexes. Further, transmetallation to cobalt complexes were achieved. Intramolecular hydroamination was measured for several chiral bis and tris amido CCC-NHC pincer zirconium catalysts. Variants of these catalytic systems were generated with differing steric hinderance and electronic structure. The enantioselectivity of these novel new molecules were studied.