Cellular and Animal Models in Human Genomics Research

Cellular and Animal Models in Human Genomics Research
Author :
Publisher : Academic Press
Total Pages : 228
Release :
ISBN-10 : 9780128165744
ISBN-13 : 012816574X
Rating : 4/5 (74X Downloads)

Book Synopsis Cellular and Animal Models in Human Genomics Research by :

Download or read book Cellular and Animal Models in Human Genomics Research written by and published by Academic Press. This book was released on 2019-07-30 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular and Animal Models in Human Genomics Research provides an indispensable resource for applying comparative genomics in the annotation of disease-gene associated variants that are identified by human genomic sequencing. The book presents a thorough overview of effective protocols for the use of cellular and animal modeling methods to turn lists of plausible genes into causative biomarkers. With chapters written by international experts, the book first addresses the fundamental aspects of using cellular and animal models in genetic and genomic studies, including in-depth examples of specific models and their utility, i.e., yeast, worms, flies, fish, mice and large animals. Protocols for properly conducting model studies, genomic technology, modeling candidate genes vs. genetic variants, integrative modeling, utilizing induced pluripotent stem cells, and employing CRISPR-Cas9 are also discussed in-depth. - Provides a thorough, accessible resource that helps researchers and students employ cellular and animal models in their own genetic and genomic studies - Offers guidance on how to effectively interpret the results and significance of genetic and genomic model studies for human health - Features chapters from international experts in the use of specific cellular and animal models, including yeast, worms, flies, fish, mice, and large animals, among other organisms


Cellular and Animal Models in Human Genomics Research Related Books

Cellular and Animal Models in Human Genomics Research
Language: en
Pages: 228
Authors:
Categories: Medical
Type: BOOK - Published: 2019-07-30 - Publisher: Academic Press

DOWNLOAD EBOOK

Cellular and Animal Models in Human Genomics Research provides an indispensable resource for applying comparative genomics in the annotation of disease-gene ass
Animal Models for the Study of Human Disease
Language: en
Pages: 1109
Authors: P. Michael Conn
Categories: Science
Type: BOOK - Published: 2013-05-29 - Publisher: Academic Press

DOWNLOAD EBOOK

Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of hum
Animal Models in Diabetes Research
Language: en
Pages: 0
Authors: Hans-Georg Joost
Categories: Science
Type: BOOK - Published: 2012-08-15 - Publisher: Humana Press

DOWNLOAD EBOOK

In recent years, human studies have made enormous contributions towards an understanding of the genetic basis of diabetes mellitus; however, most of the experim
Experimental and Quasi-Experimental Designs for Research
Language: en
Pages: 172
Authors: Donald T. Campbell
Categories: Psychology
Type: BOOK - Published: 2015-09-03 - Publisher: Ravenio Books

DOWNLOAD EBOOK

We shall examine the validity of 16 experimental designs against 12 common threats to valid inference. By experiment we refer to that portion of research in whi
Improving the Utility and Translation of Animal Models for Nervous System Disorders
Language: en
Pages: 111
Authors: Institute of Medicine
Categories: Medical
Type: BOOK - Published: 2013-04-25 - Publisher: National Academies Press

DOWNLOAD EBOOK

Nervous system diseases and disorders are highly prevalent and substantially contribute to the overall disease burden. Despite significant information provided