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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 442C: In Chemico Skin Sensitisation Assays addressing the Adverse Outcome Pathway key event on covalent binding to proteins
Language: en
Pages: 63

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 442C: In Chemico Skin Sensitisation Assays addressing the Adverse Outcome Pathway key event on covalent binding to proteins

Authors: OECD
Categories:
Type: BOOK - Published: 2015-02-05 - Publisher: OECD Publishing

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This Test Guideline addresses the human health hazard endpoint skin sensitisation, following exposure to a test chemical. It provides an in chemico procedure (D
Hayes' Principles and Methods of Toxicology
Language: en
Pages: 2143

Hayes' Principles and Methods of Toxicology

Authors: A. Wallace Hayes
Categories: Medical
Type: BOOK - Published: 2023-07-03 - Publisher: CRC Press

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Hayes’ Principles and Methods of Toxicology has long been established as a reliable and informative reference for the concepts, methodologies, and assessments
Chemical Testing Using New Approach Methodologies (NAMs)
Language: en
Pages: 139

Chemical Testing Using New Approach Methodologies (NAMs)

Authors: Amy J. Clippinger
Categories: Science
Type: BOOK - Published: 2022-12-16 - Publisher: Frontiers Media SA

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European Partnership on the Assessment of Risks from Chemicals (PARC): Focus on New Approach Methodologies (NAMs) in Risk Assessment
Language: en
Pages: 125

European Partnership on the Assessment of Risks from Chemicals (PARC): Focus on New Approach Methodologies (NAMs) in Risk Assessment

Authors: Terje Svingen
Categories: Medical
Type: BOOK - Published: 2024-08-21 - Publisher: Frontiers Media SA

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The European Partnership on the Assessment of Risks from Chemicals (PARC) project was launched in 2022. The overarching aim of this partnership is to enhance ou
OECD Guidelines for the Testing of Chemicals, Section 4 Guideline No. 497: Defined Approaches on Skin Sensitisation
Language: en
Pages: 53

OECD Guidelines for the Testing of Chemicals, Section 4 Guideline No. 497: Defined Approaches on Skin Sensitisation

Authors: OECD
Categories:
Type: BOOK - Published: 2023-07-04 - Publisher: OECD Publishing

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A Defined Approach (DA) consists of a selection of information sources (e.g in silico predictions, in chemico, in vitro data) used in a specific combination, an