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Mutagenicity: Assays and Applications
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Authors: Ashutosh Kumar
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Mutagenicity: Assays and Applications presents an extensive examination of the detection, assessment and future of mutagenicity, particularly as it concerns hum
Mutagenic Impurities
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Type: BOOK - Published: 2022-02-15 - Publisher: John Wiley & Sons

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Learn to implement effective control measures for mutagenic impurities in pharmaceutical development In Mutagenic Impurities: Strategies for Identification and
Test No. 488: Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays
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This Test Guideline describes an in vivo assay that detects chemicals that may induce gene mutations. In this assay, transgenic rats or mice that contain multip
Test No. 483: Mammalian Spermatogonial Chromosomal Aberration Test
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This test measures structural chromosomal aberrations (both chromosome- and chromatid-type) in dividing spermatogonial germ cells and is, therefore, expected to
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 471: Bacterial Reverse Mutation Test
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The bacterial reverse mutation test uses amino-acid requiring at least five strains of Salmonella typhimurium and Escherichia coli to detect point mutations by